Photos by Baruch Herzfeld: Cars involved in a collision on FDR Drive were towed to Delancey Street between Ridge and Pitt Streets.

A driver heading the wrong way on FDR Drive led to a three-car pileup that left two dead and two others injured early Sunday morning.

The police said that a 26-year-old man was driving a Nissan Maxima at 2:52 a.m. against southbound traffic when he collided with a Dodge Caravan. A Mazda then collided with the wreck near Houston Street, injuring the 22-year-old driver, as well as her 31-year-old passenger.

The 52-year-old driver of the Caravan and the driver of the Maxima were both pronounced dead at the scene. The passengers of the Mazda were taken to Bellevue Hospital in stable condition, the police said. The police have not yet released the names of the victims.